HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Chloro-6-iodo-1,3-dihydro-isoindole-2-carboxylic Acid Tert-Butyl Ester → 5-Chloro-6-(2,5-dihydro-furan-3-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Chloro-6-iodo-1,3-dihydro-isoindole-2-carboxylic Acid Tert-Butyl Ester | HCID 57753455 | — |
| Reactant | Tributyl-(2,5-dihydro-furan-3-yl)-stannane | HCID 68822896 | — |
| Product | 5-Chloro-6-(2,5-dihydro-furan-3-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester | HCID 57753228 | — |
Reaction Steps
Prepared in analogy to Example A49(a) from 5-chloro-6-iodo-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester (Example A3(c)) and tributyl-(2,5-dihydro-furan-3-yl)-stannane. Off-white solid. MS (m/e): 268.3 ([{37Cl} M+H−Me2C═CH2]+, 32%), 266.1 ([{35Cl}M+H−Me2C═CH2]+, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07557114B2 |
| Source dataset | uspto-grants-2009_07 |
| ORD ID | ord-725c82d9e5774fcf9135d236da4fab51 |
| Source note | uspto-grants-2009_07 |