Hydrochloric Acid → HCID 19698841, compound

Participants

Reaction Steps

Add 1N HCl in methanol (50 ml) to 1,17-diethyl-2,16-dimethyl-1,5,13,17-tetra(t-butoxycarbonyl)-1,5,13,17-tetraazaheptadecane (3.9 g, 0.0054 mol) and stir overnight. Remove the solvent in vacuo and recrystallize the residue two times from methanol/acetonitrile (40/60, v/v) to yield 0.90 g of the title compound as a white solid (mp 249°-50 ° C.). Rf is 0.56 for TLC on silica gel developed with 40% conc. ammonia in methanol.

Provenance & Evidence