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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 225665Generated: October 25, 2026

3-Oxa-8-azabicyclo(3.2.1)octane hydrochloride → HCID 57753727, compound

https://huagongshe.com/reaction/225665

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Oxa-8-azabicyclo(3.2.1)octane hydrochlorideHCID 53401129—
Reactant5-Chloro-6-iodo-1,3-dihydro-isoindole-2-carboxylic Acid Tert-Butyl EsterHCID 57753455—
ProductHCID 57753727HCID 57753727—

Reaction Steps

Prepared in analogy to Example A3(d) from 5-chloro-6-iodo-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester (Example A3(c)) and 3-oxa-8-azabicyclo[3.2.1]octane hydrochloride. Yellow solid. MS (m/e): 367.1 ([{37Cl}M+H]+, 35%), 365.1 ([{35Cl}M+H]+, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07557114B2
Source datasetuspto-grants-2009_07
ORD IDord-6bcb253f43724da78b80445a9170d4d0
Source noteuspto-grants-2009_07