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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 225667Generated: October 30, 2026

5-Chloro-6-iodo-1,3-dihydro-isoindole-2-carboxylic Acid Tert-Butyl Ester → HCID 68822122, compound

https://huagongshe.com/reaction/225667

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Chloro-6-iodo-1,3-dihydro-isoindole-2-carboxylic Acid Tert-Butyl EsterHCID 57753455—
ReactantHCID 68824959HCID 68824959—
ProductHCID 68822122HCID 68822122—

Reaction Steps

Prepared in analogy to Example A3(d) from 5-chloro-6-iodo-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester (Example A3(c)) and (1S,4S)-2-oxa-5-aza-bicyclo[2.2.1]heptane trifluoroacetate. Light yellow solid. MS (m/e): 353.1 ([{37Cl}M+H]+, 36%), 351.1 ([{35Cl}M+H]+, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07557114B2
Source datasetuspto-grants-2009_07
ORD IDord-b6a2d3b770674711ba7c7e011cac0c9c
Source noteuspto-grants-2009_07