HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diphosgene → HCID 57259964, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diphosgene | HCID 10426 | — |
| Reactant | HCID 10998605 | HCID 10998605 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 57259964 | HCID 57259964 | — |
Reaction Steps
To a solution of benzyl (2S)-2-hydroxy-4-methylvalerate (1.00 g) in tetrahydrofuran (20 ml) was added trichloromethyl chloroformate (0.55 ml) at room temperature. The solution was refluxed for 11 hours and the solvent was removed by evaporation at atmospheric pressure to give benzyl (2S)-2-chlorocarbonyloxy-4-methylvalerate (1.26 g) as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05656604 |
| Source dataset | uspto-grants-1997_08 |
| ORD ID | ord-a15b7fbd78994cc4b8bd28ad04520ce7 |
| Source note | uspto-grants-1997_08 |