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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 225684Generated: October 26, 2026

Trifluoroacetic acid → 5-(3,3,3-Trifluoro-propoxy)-2,3-dihydro-1H-isoindole trifluoroacetate

https://huagongshe.com/reaction/225684

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactant5-(3,3,3-Trifluoro-propoxy)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl esterHCID 57753429—
Product5-(3,3,3-Trifluoro-propoxy)-2,3-dihydro-1H-isoindole trifluoroacetateHCID 86607010—

Reaction Steps

Prepared in analogy to Example A2(c) from 5-(3,3,3-trifluoro-propoxy)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester and trifluoroacetic acid. Brown oil. MS (m/e): 232.1 ([M+H]+, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07557114B2
Source datasetuspto-grants-2009_07
ORD IDord-854abd7d48d543c1a15036aff4e3b39c
Source noteuspto-grants-2009_07