4-sec-Butylphenol → N-(Isoquinolin-5-yl)-2-(4-(1-methylpropyl)phenoxy)nonanoic amide

HRID 2257163Notes

Reaction equation

HRID 2257163 reaction equation
[CH:1]1[C:10]2[C:5](=[C:6]([NH:11][C:12](=[O:23])[CH:13](Br)[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]C)[CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][N:2]=1.[CH3:24][CH:25]([C:28]1[CH:33]=[CH:32][C:31]([OH:34])=[CH:30][CH:29]=1)[CH2:26][CH3:27]>>[CH:1]1[C:10]2[C:5](=[C:6]([NH:11][C:12](=[O:23])[CH:13]([O:34][C:31]3[CH:32]=[CH:33][C:28]([CH:25]([CH3:24])[CH2:26][CH3:27])=[CH:29][CH:30]=3)[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])[CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][N:2]=1

Participants

3

Reactant 2

HCID 74534-sec-ButylphenolHCID 14995543N-(isoquinolin-5-yl)-2-bromodecanoic amide

Product 1

HCID 14995410N-(Isoquinolin-5-yl)-2-(4-(1-methylpropyl)phenoxy)nonanoic amide

Procedure

N-(isoquinolin-5-yl)-2-bromodecanoic amide, prepared according to the procedures described in Example 3 and 25, was coupled with 4-(1-methylpropyl)phenol according to the procedure described in Example 6 to give the title compound.

Sources & evidence

ORD record
ord-9058e9da71264e40910e1f6624200a3d
Source dataset
uspto-grants-1997_08
Patent number
US05656634

Reaction notes

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