HCID 10036516, compound → HCID 14995418, compound

HRID 2257167Notes

Reaction equation

HRID 2257167 reaction equation
[CH3:1][C:2]1[CH:3]=[N:4][C:5]2[C:10]([C:11]=1Cl)=[C:9]([N+:13]([O-])=O)[CH:8]=[CH:7][CH:6]=2>[Pd]>[CH3:1][C:2]1[CH:3]=[N:4][C:5]2[C:10]([CH:11]=1)=[C:9]([NH2:13])[CH:8]=[CH:7][CH:6]=2

Participants

3

Reactant 1

HCID 10036516HCID 10036516, compound

Product 1

HCID 14995418HCID 14995418, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

3-Methyl-4-chloro-5-nitroquinoline was hydrogenated using Pd/C to give 3-methyl-5-aminoquinoline. This material was coupled with 2-(4-(1-methylpropyl)phenoxy) nonanoic acid according to the procedure outlined in Example 25 to give the title compound.

Sources & evidence

ORD record
ord-59fc736dfd8349eb9cff6f52dd49e178
Source dataset
uspto-grants-1997_08
Patent number
US05656634

Reaction notes

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