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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2257175Generated: October 30, 2026

Iodoethane → Ethyl 6-quinolyl ether

https://huagongshe.com/reaction/2257175

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIodoethaneHCID 6340—
Reactant6-HydroxyquinolineHCID 11374—
ReactantSodium hydrideHCID 24758—
ProductEthyl 6-quinolyl etherHCID 89883—

Reaction Steps

6-Hydroxyquinoline was treated with sodium hydride and ethyl iodide to give 6-ethoxyquinoline. This material was nitrated, reduced and coupled with 2-hexylthiodecanoic acid according to the procedure of Example 33 to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05656634
Source datasetuspto-grants-1997_08
ORD IDord-fab88e9b67684efa939c683bf1221a8f
Source noteuspto-grants-1997_08