Oleoyl chloride → HCID 67710037, compound

HRID 2257198Notes

Reaction equation

HRID 2257198 reaction equation
[NH2:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[C:4]([Br:12])=[CH:5][N:6]=[CH:7]2.[C:13](Cl)(=[O:31])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]/[CH:21]=[CH:22]\[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30]>>[Br:12][C:4]1[C:3]2[C:8](=[CH:9][CH:10]=[CH:11][C:2]=2[NH:1][C:13](=[O:31])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20]/[CH:21]=[CH:22]\[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH3:30])[CH:7]=[N:6][CH:5]=1

Participants

3

Reactant 2

HCID 5364783Oleoyl chlorideHCID 145800574-Bromoisoquinolin-5-amine

Product 1

HCID 67710037HCID 67710037, compound

Procedure

5-Amino-4-bromoisoquinoline (prepared according to the process described by Gordon et al., J. Het. Chem., 4, 410 (1967)) was coupled with oleoyl chloride using the procedure described in Example 4, to give the title compound.

Sources & evidence

ORD record
ord-a4cce1e7d8a74dfa81862903d3393510
Source dataset
uspto-grants-1997_08
Patent number
US05656634

Reaction notes

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