HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Methylthio)phenylacetyl chloride → 4-(4-Methylthiophenylacetyl)-3-(pyrrolidin-1-ylmethyl)thiomorpholine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Methylthio)phenylacetyl chloride | HCID 15020187 | — |
| Reactant | 3-(Pyrrolidin-1-ylmethyl)thiomorpholine | HCID 15730147 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | 4-(4-Methylthiophenylacetyl)-3-(pyrrolidin-1-ylmethyl)thiomorpholine hydrochloride | HCID 67625298 | — |
Reaction Steps
The procedure described in Example 17 was repeated, but using 1.0 g of 3-(pyrrolidin-1-ylmethyl)thiomorpholine, 1.38 ml of triethylamine and 1.2 of 4-methylthiophenylacetyl chloride, to afford 1.38 g of the title compound, melting at 162°-166° C. (dec.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05656758 |
| Source dataset | uspto-grants-1997_08 |
| ORD ID | ord-a3fb9a01a23549d78f8cd38cc4a058d6 |
| Source note | uspto-grants-1997_08 |