(3,5-Difluorophenyl)boronic acid → HCID 57753575, compound

HRID 225732Notes

Reaction equation

HRID 225732 reaction equation
I[C:2]1[CH:10]=[CH:9][C:8]([S:11]([CH3:14])(=[O:13])=[O:12])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].[F:15][C:16]1[CH:17]=[C:18](B(O)O)[CH:19]=[C:20]([F:22])[CH:21]=1>>[F:15][C:16]1[CH:17]=[C:18]([C:2]2[C:3]([C:4]([OH:6])=[O:5])=[CH:7][C:8]([S:11]([CH3:14])(=[O:13])=[O:12])=[CH:9][CH:10]=2)[CH:19]=[C:20]([F:22])[CH:21]=1

Participants

3

Reactant 2

HCID 2734338(3,5-Difluorophenyl)boronic acidHCID 574452812-Iodo-5-methanesulfonyl-benzoic acid

Product 1

HCID 57753575HCID 57753575, compound

Procedure

Prepared in analogy to Example B25 from 2-Iodo-5-methanesulfonyl-benzoic acid (example B19(b)) and 3,5-difluoro-benzeneboronic acid. Light brown solid. MS (m/e): 311.1 ([M−H], 100%).

Sources & evidence

ORD record
ord-39a72b43146b43a29ea42b478b08fb4f
Source dataset
uspto-grants-2009_07
Patent number
US07557114B2

Reaction notes

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