L-Serine → L-Serine

Participants

Reaction Steps

The copolymers in Table 3 were prepared from the thermal condensation of amino acids. For each copolymer in Table 3 (Examples 18-28), the amino acids were thermally condensed in the proportions of 80 moles of the first amino acid shown in Table 3, under "Scale Inhibitor" (i.e., aspartic acid) to 20 moles of the second amino acid shown in Table 3 to form a reaction product. In Example 27, the proportions of amino acids condensed were 80 moles of aspartic acid to 20 moles of serine; however, a reaction product of aspartic acid, serine, and d-alanine formed in the proportions shown in Table 3. In Examples 18-28, the thermal condensation reaction was performed using an acid catalyst. Polyphosphoric acid was used in Examples 18-25 and 27°-28, and orthophosphoric acid was used in Example 26. After the reaction was complete, the acid catalyst was completely removed from the reaction product by washing with water. The reaction product was purified by dialysis, and then hydrolyzed at a pH of 10.8, with sodium hydroxide, at 90° C. over 30 minutes.

Provenance & Evidence