HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,5-Dibromopentane → 5-Octyl-2-[4-(5-(2-(2-(2-(trifluoromethoxy)tetrafluoroethoxy)tetrafluoroethoxy)-2,2-difluoroethoxy)pentyloxy)phenyl]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,5-Dibromopentane | HCID 8100 | — |
| Reactant | 2-(4-Hydroxyphenyl)-5-octylpyrimidine | HCID 604055 | — |
| Reactant | 1H,1H-Tridecafluoro-3,6,9-trioxadecan-1-ol | HCID 2778161 | — |
| Reactant | 5-(2-(2-(2-(Trifluoromethoxy)tetrafluoroethoxy)tetrafluoroethoxy)-2,2-difluoroethoxy)1-bromopentane | HCID 21225274 | — |
| Product | 5-Octyl-2-[4-(5-(2-(2-(2-(trifluoromethoxy)tetrafluoroethoxy)tetrafluoroethoxy)-2,2-difluoroethoxy)pentyloxy)phenyl]pyrimidine | HCID 21225408 | — |
Reaction Steps
The title compound was prepared essentially as in Example 1 by combining 5-(2-(2-(2-(trifluoromethoxy)tetrafluoroethoxy)tetrafluoroethoxy)-2,2-difluoroethoxy)1-bromopentane (18.3 g, 38.5 mmol; prepared from 1,5-dibromopentane (107 g, 0.7 mol) and 2-(2-(2-(trifluoromethoxy)tetrafluoroethoxy)tetrafluoroethoxy)-2,2-difluoroethanol (125 g, 0.31 mol) essentially as in Example 2 ) with 5-octyl-2-(4-hydroxyphenyl)pyrimidine (10 g, 35 mmol) to provide product boiling at 200°-210° C. at 0.4 torr (yield of 20.8 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05658491 |
| Source dataset | uspto-grants-1997_08 |
| ORD ID | ord-0c8e7299f87e407690e660e3fa4fbdac |
| Source note | uspto-grants-1997_08 |