Chloride → HCID 22923047, compound

Participants

Reaction Steps

The 1,2-dihydro-4-methyl-1-phenyl-2-quinolone is heated at reflux with 1.3 equivalents of phosphorus oxychloride and 1 equivalent of DMF in toluene for one hour to generate the 2-chloro-4-methyl-1-phenylquinolinium chloride (3). The chloride is then stirred in the corresponding dimethylaminoethanethiol in methylene chloride to produce the corresponding 2-dimethylaminoethylthio-1-phenylquinolinium chloride. This is then reacted with one equivalent each of the 2-(2-anilinovinyl)-3-methyl-benzoxazolium tosylate, triethylamine and acetic anhydride to generate the corresponding trimethine derivative.

Provenance & Evidence