HuagongsheHuagongshe Chemistry Print Report · For research reference only
Beta-Alanine → rac-(1R,3S)-3-aminocyclohexane-1-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Beta-Alanine | HCID 239 | — |
| Reactant | N,N,N-trimethylglycinium | HCID 248 | — |
| Reactant | Guvacine | HCID 3532 | — |
| Reactant | Nipecotic Acid | HCID 4498 | — |
| Reactant | L-2,4-Diaminobutyric acid | HCID 134490 | — |
| Reactant | HCID 178518980 | HCID 178518980 | — |
| Product | rac-(1R,3S)-3-aminocyclohexane-1-carboxylic acid | HCID 7005079 | — |
Reaction Steps
[3H]GABA3 (98.9 Ci/mmole) was obtained from New England Nuclear (Boston, Mass.). β-alanine, betaine and L-DABA (L-(2,4) diaminobutyric acid) were from Sigma Chemical Company (St. Louis, Mo.); guvacine, nipecotic acid, OH-nipecotic (hydroxynipecotic acid), and THPO (4,5,6,7-tetrahydroisoxazolo (4,5-c]pyridin-3-ol) were from RBI (Natick, Mass.). ACHC (cis-3-aminocyclohexanecarboxylic acid) was kindly provided by Drs. Richard Milius and William White of the NIgH Chemical Synthesis Program.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05658786 |
| Source dataset | uspto-grants-1997_08 |
| ORD ID | ord-c3d8464b3e0f4cc59bc7a4ef77c0d2bc |
| Source note | uspto-grants-1997_08 |