2-Methoxyphenethylamine → HCID 19704106, compound

Participants

Reaction Steps

A solution of 1,1'-thiocarbonyldiimidazole (1.78 g, 10 mmol) and 2-methoxyphenethylamine (1.51 g, 10 mmol) in acetonitrile 25 mL) was stirred at room temperature for 20 h. The resulting precipitate was collected by filtration to provide 1.40 g (53%) of the titled product: IR (KBr, cm-1) 2944, 1563, 1493, 1409, 1282, 1246, 1031, 755; 1H NMR (300 MHz, DMSO-d6) δ 12.0 (br s, 1H), 7.65 (s, 1H), 7.25 (m, 2H), 7.05-6.9 (m, 4H), 3.8 (m, 2H), 3.8 (s, 3H), 2.95 (t, J=7 Hz, 2H); MS (FD) m/e 261 (M+); UV (EtOH) 278 nm (ε=7083), 216 nm (ε=12683), 203 nm (ε=22221).

Provenance & Evidence