HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4,5-Trimethoxybenzonitrile → 3,4,5-Trimethoxybenzylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4,5-Trimethoxybenzonitrile | HCID 15892 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Catalyst | Cobalt(II) chloride | HCID 24288 | — |
| Product | 3,4,5-Trimethoxybenzylamine | HCID 87736 | — |
Reaction Steps
The starting material 3,4,5-trimethoxybenzylamine was prepared by reduction of 3,4,5-trimethoxybenzonitrile with cobalt chloride and sodium borohydride, according to the general method described by L. S. Heinzman in J. Am. Chem. Soc., 104, p. 6801 (1980).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05658907 |
| Source dataset | uspto-grants-1997_08 |
| ORD ID | ord-fb78f195e4e144138aaea7adf7e397d3 |
| Source note | uspto-grants-1997_08 |