Acetone → HCID 86750958, compound

HRID 2257827Notes

Reaction equation

HRID 2257827 reaction equation
[C:1]([NH:4][CH:5]1[CH2:14][CH2:13][C:12]2[C:7](=[C:8]([O:19][CH3:20])[CH:9]=[CH:10][C:11]=2[NH:15][C:16](=[O:18])[CH3:17])[CH2:6]1)(=[O:3])[CH3:2].CC(C)=[O:23].S([O-])([O-])(=O)=O.[Mg+2].[Mn]([O-])(=O)(=O)=O.[K+]>O>[C:1]([NH:4][CH:5]1[CH2:6][C:7]2[C:12](=[C:11]([NH:15][C:16](=[O:18])[CH3:17])[CH:10]=[CH:9][C:8]=2[O:19][CH3:20])[C:13](=[O:23])[CH2:14]1)(=[O:3])[CH3:2]

Participants

6

Reactant 4

HCID 180AcetoneHCID 24083Sulfuric acid magnesium salt (1:1)HCID 516875Potassium PermanganateHCID 86750959HCID 86750959, compound

Product 1

HCID 86750958HCID 86750958, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

190 mg of the compound prepared in (3) above was suspended into a mixture of 16 ml of acetone and 4 ml of 15% aqueous solution of magnesium sulfate, and to the solution was added 543 mg of potassium permanganate, followed by stirring for 1.5 hours at room temperature. After the addition of 150 ml of water, the reaction mixture was extracted withe chloroform. The extract was waxhed with saturated brine and dried over magnesium sulfate. After removal of the solvent, the residue was ctystallized in ethyl acetate and hexane to produce 124 mg of the title compound.

Workup

  1. extractionthe reaction mixture was extracted withe chloroform
  2. dry with materialdried over magnesium sulfate
  3. customAfter removal of the solvent

Sources & evidence

ORD record
ord-44df7bdbf7184c7289e9cb65a5497dfc
Source dataset
uspto-grants-1997_08
Patent number
US05658920

Reaction notes

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