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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2257865Generated: October 27, 2026

N-(8-Oxo-5,6,7,8-tetrahydronaphthalen-1-YL)acetamide → 1-Acetyl-3,5-diacetylamino-8-chloro-2,3-dihydro-quinoline-4-one

https://huagongshe.com/reaction/2257865

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(8-Oxo-5,6,7,8-tetrahydronaphthalen-1-YL)acetamideHCID 12119265—
Reactant1-Acetyl-5-acetylamino-8-chloro-2,3-dihydroquinoline-4-oneHCID 22449421—
Product1-Acetyl-3,5-diacetylamino-8-chloro-2,3-dihydro-quinoline-4-oneHCID 22449510—

Reaction Steps

The reaction was carried out in the same manner as in Example 1-(2), except that 1.4 gm of the compound prepared in (1) above was used instead of 8-acetylamino-1-tetralone of Example 1-(2). The reaction mixture obtained by the post-treatment was further reacted in the same manner as in Example 1-(3) and post-treated to produce 0.62 gm of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05658920
Source datasetuspto-grants-1997_08
ORD IDord-3ab6b4effac847b191567138211419e9
Source noteuspto-grants-1997_08