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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2257998Generated: November 2, 2026

Hydrochloric Acid → {3-[4-(aminoiminomethyl)benzyl]-2,5-dioxopyrrolidin-1-yl}acetyl-D,L-homophenylalanine

https://huagongshe.com/reaction/2257998

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant{3-[4-(Aminoiminomethyl)benzyl]-2,5-dioxopyrrolidin-1-yl}acetyl-D,L-homophenylalanine methyl esterHCID 131720120—
Product{3-[4-(aminoiminomethyl)benzyl]-2,5-dioxopyrrolidin-1-yl}acetyl-D,L-homophenylalanineHCID 13172012155%

Reaction Steps

45 mg of {3-[4-(aminoiminomethyl)benzyl]-2,5-dioxopyrrolidin-1-yl}acetyl-D,L-homophenylalanine methyl ester are allowed to stand at room temperature for 1 h with 5 ml of concentrated hydrochloric acid. The mixture is then concentrated to dryness in vacuo, and the residue is taken up in a little water and freeze-dried. 24 mg of {3-[4-(aminoiminomethyl)benzyl]-2,5-dioxopyrrolidin-1-yl}acetyl-D,L-homophenylalanine are obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05658935
Source datasetuspto-grants-1997_08
ORD IDord-84d2c53eb5184f3bbb78ce998b973d01
Source noteuspto-grants-1997_08