HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2258024Generated: October 28, 2026
p-Toluenesulfonic acid → HCID 131720122, compound
https://huagongshe.com/reaction/2258024
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | Ethyl nitroacetate | HCID 69379 | — |
| Reactant | Bis(1,3-benzodioxol-5-yl)methanol | HCID 384225 | — |
| Product | HCID 131720122 | HCID 131720122 | 79% |
Reaction Steps
The alcohol of Example 17 is dissolved in 5 mL of nitro ethyl acetate. A catalytic amount of p-toluene-sulfonic acid is added and the reaction mixture is heated to 120° C. for 3 hours. Excess nitro ethyl acetate is removed by distillation and the residue is purified by silica gel chromatography eluting with 15% ethyl acetate-hexane to give 2.25 g (79%) of product as a yellow oil;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05658943 |
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| Source dataset | uspto-grants-1997_08 |
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| ORD ID | ord-0babcdc36c5440519f44d51a4bc2bd96 |
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| Source note | uspto-grants-1997_08 |
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