HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Iodopyridine-3-carboxylic acid → Ethyl6-iodonicotinoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Iodopyridine-3-carboxylic acid | HCID 819062 | — |
| Reactant | Ethyl 6-chloronicotinate | HCID 2799611 | — |
| Reactant | Triethylorthoaceate | HCID 21875354 | — |
| Product | Ethyl6-iodonicotinoate | HCID 10891136 | 92.4% |
Reaction Steps
Using the same procedure for ethyl 6-chloronicotinate but instead using 6-iodonicotinic acid (7.14 g, 28.67 mmol) and triethylorthoacetate (13.96 g, 86.02 mmol) gave the titled compound as a white solid (7.340 g, 26.49 mmol, 92.4%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05659042 |
| Source dataset | uspto-grants-1997_08 |
| ORD ID | ord-9ee0f62c925f46d19306e35bb46e2deb |
| Source note | uspto-grants-1997_08 |