HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Nitroimidazole → (S)-(+)-alpha-(chloromethyl)-2-nitro-1H-imidazole-1-ethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Nitroimidazole | HCID 10701 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | (+)-Epichlorohydrin | HCID 149428 | — |
| Product | (S)-(+)-alpha-(chloromethyl)-2-nitro-1H-imidazole-1-ethanol | HCID 11052772 | — |
Reaction Steps
Alternatively, reaction of 2-nitroimidazole, anhydrous potassium carbonate, and (S)-(+)-epichlorhydrin as described in Example 1 (a) gives the product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05659048 |
| Source dataset | uspto-grants-1997_08 |
| ORD ID | ord-4d83fcd4cb284fee8ed95eb033958ea0 |
| Source note | uspto-grants-1997_08 |