3-Hydroxypicolinic Acid → HCID 22923820, compound

HRID 2258306Notes

Reaction equation

HRID 2258306 reaction equation
[OH:1][C:2]1[C:3]([C:8]([OH:10])=[O:9])=[N:4][CH:5]=[CH:6][CH:7]=1.[CH3:11][O:12][C:13]1[CH:14]=[C:15]([CH:18]=[CH:19][CH:20]=1)[CH2:16]Cl>>[CH3:11][O:12][C:13]1[CH:14]=[C:15]([CH:18]=[CH:19][CH:20]=1)[CH2:16][O:1][C:2]1[C:3]([C:8]([O:10][CH2:16][C:15]2[CH:18]=[CH:19][CH:20]=[C:13]([O:12][CH3:11])[CH:14]=2)=[O:9])=[N:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 134013-Hydroxypicolinic AcidHCID 699943-Methoxybenzyl chloride

Product 1

HCID 22923820HCID 22923820, compound

Procedure

In analogy with Example 38a), 10 g of the product were obtained, as a colorless oil which was subjected to further reaction, from 8.4 g (60 mmol) of 3-hydroxypyridine-2-carboxylic acid and 3-methoxybenzyl chloride following chromatography on silica gel.

Sources & evidence

ORD record
ord-ccd8d8525cf64607850811c496f52ae4
Source dataset
uspto-grants-1997_08
Patent number
US05658933

Reaction notes

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