Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzoyl Peroxide → 2-(Bromomethyl)-7-chloroquinoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzoyl Peroxide | HCID 7187 | — |
| 반응물 | N-bromobutanimide | HCID 67184 | — |
| 반응물 | 7-Chloro-2-methylquinoline | HCID 138395 | — |
| 용매 | Carbon Tetrachloride | HCID 5943 | — |
| 생성물 | 2-(Bromomethyl)-7-chloroquinoline | HCID 10244160 | — |
반응 단계
A stirred suspension of N-bromosuccinimide (9.0 g), 7-chloroquinaldine (9.0 g), dibenzoylperoxide (0.5 g ) in CCl4 (200 ml) at 90° was illuminated with a 225W sunlamp for 6 hours. The suspension was cooled and passed through a plug of silica gel. The plug of silica gel was washed with 30% ether in hexane and the filtrate was evaporated. Flash chromatography of the residue using 30% ether in hexane afforded the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05428171 |
| 출처 데이터셋 | uspto-grants-1995_06 |
| ORD ID | ord-fbd00b5413db49c0a6a962721018cef8 |
| 출처 메모 | uspto-grants-1995_06 |