HuagongsheHuagongshe Chemistry Print Report · For research reference only
di t-butyl 4-nitrobenzylcarbonyl-L-glutamate → di t-butyl 4-aminobenzylcarbonyl-L-glutamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | di t-butyl 4-nitrobenzylcarbonyl-L-glutamate | HCID 86748613 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | di t-butyl 4-aminobenzylcarbonyl-L-glutamate | HCID 86748612 | — |
Reaction Steps
A solution of di t-butyl 4-nitrobenzylcarbonyl-L-glutamate (9.7 g) in ethyl acetate (200 ml) was hydrogenated over 30% Pd/C (900 mg). The mixture was then filtered through Celite and evaporated to yield a yellow oil (di t-butyl 4-aminobenzylcarbonyl-L-glutamate) which was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05660829 |
| Source dataset | uspto-grants-1997_08 |
| ORD ID | ord-1251c4b5cda14b64b7b01a3c26a727d2 |
| Source note | uspto-grants-1997_08 |