HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 8-chloro-N-[4-(4-pyridinyl)butyl]dibenz[b,f][1,4]oxazepine-10(11H)-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-(Pyridin-4-yl)butan-1-amine | HCID 13557532 | — |
| Reactant | 8-chlorodibenz[b,f][1,4]oxazepin-10(11H)carbonyl chloride | HCID 14975983 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 8-chloro-N-[4-(4-pyridinyl)butyl]dibenz[b,f][1,4]oxazepine-10(11H)-carboxamide | HCID 9801539 | 60.9% |
Reaction Steps
By the method described in Example 18, the title compound of Example 2 (0.98 g, 3.3 mmol) in 30 mL of CH2Cl2 with molecular sieves #5A (3 g) and Et3N (0.47 mL, 3.36 mmol) was reacted with the title compound of Example 23 (0.5 g, 3.3 mmol) to produce 0.82 g of the title product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05661146 |
| Source dataset | uspto-grants-1997_08 |
| ORD ID | ord-b8a56a817d414c84b0259449a9a6a31c |
| Source note | uspto-grants-1997_08 |