3,4-Dinitrobenzoic acid → 5-(3,4-Dinitrobenzoyloxy)-4-methoxy-2,6,6-trimethyl-2-cyclohepten-1-one

HRID 2258503ノート

反応式

HRID 2258503 の反応式
[OH:1][CH:2]1[C:8]([CH3:10])([CH3:9])[CH2:7][C:6](=[O:11])[C:5]([CH3:12])=[CH:4][CH:3]1[O:13][CH3:14].[N+:15]([C:18]1[CH:19]=[C:20]([CH:24]=[CH:25][C:26]=1[N+:27]([O-:29])=[O:28])[C:21](O)=[O:22])([O-:17])=[O:16]>>[N+:15]([C:18]1[CH:19]=[C:20]([CH:24]=[CH:25][C:26]=1[N+:27]([O-:29])=[O:28])[C:21]([O:1][CH:2]1[C:8]([CH3:9])([CH3:10])[CH2:7][C:6](=[O:11])[C:5]([CH3:12])=[CH:4][CH:3]1[O:13][CH3:14])=[O:22])([O-:17])=[O:16]

参加物

3

反応物 2

HCID 107093,4-Dinitrobenzoic acidHCID 229223715-Hydroxy-4-methoxy-2,6,6-trimethyl-2-cyclohepten-1-one

生成物 1

HCID 229224175-(3,4-Dinitrobenzoyloxy)-4-methoxy-2,6,6-trimethyl-2-cyclohepten-1-one収率 85%

実験手順

5-Hydroxy-4-methoxy-2,6,6-trimethyl-2-cyclohepten-1-one (AU154) obtained in Example 4 (25.0 g, 126 mM) was treated with 3,4-dinitrobenzoic acid according to the procedures described in Example 20, and crystallized from methanol to obtain 42.1 g (85%) of 5-(3,4-dinitrobenzoyloxy)-4-methoxy-2,6,6-trimethyl-2-cyclohepten-1-one (AU409) as light yellow needles. Melting point: 103° to 104° C.

後処理

  1. customcrystallized from methanol

出典と根拠

ORDレコード
ord-dc6481f3a7814482999ebf1e9d5e128c
出典データセット
uspto-grants-1997_08
特許番号
US05661166

反応ノート

読み込み中…