Ethanol → HCID 22922427, compound

Participants

Reaction Steps

5-Hydroxy-4-(4-nitrobenzoyloxy)-2,6,6-trimethyl-2-cyclohepten-1-one (1.00 g, 3.0 mM) obtained in Example 44 was treated with ethanol (20 ml) according to the procedures described in Example 99 and crystallized from a mixed solution of ethyl acetate and hexane to obtain 0.7 g (64%) of 1-ethoxy-4-(4-nitrobenzoyloxy)-2,6,6-trimethyl-8-oxabicyclo[3.2.1]oct-2-ene (AU246) as light yellow flakes. Melting point: 144° to 146° C.

Provenance & Evidence