反应详情

To a mixture of 5-acetyl-2-(methoxycarbonyl) methoxybenzaldehyde (4.47 g) in toluene, a solution of 1,8-diazabicyclo[5.4.0]-7-undecene (1.30 g) in toluene (8 ml) was added dropwise for 15 hours at refluxing temperature. After being cooled, the resulting mixture was washed with water, dried lover magnesium sulfate and concentrated under reduced pressure. The resulting precipitates were washed with diethyl ether to give 5-acetyl-2-methoxycarbonylbenzofuran (1.65 g).

1. temperatureat refluxing temperature
2. temperatureAfter being cooled
3. washthe resulting mixture was washed with water
4. dry with materialdried lover magnesium sulfate
5. concentrationconcentrated under reduced pressure
6. customThe resulting precipitates
7. washwere washed with diethyl ether