Ethyl 4-bromobutyrate → HCID 22922146, compound

Participants

Reaction Steps

A mixture of 7-Chloro-2-(5-aminobenzofuran-2-yl)-quinoline (0.17 g), sodium bicarbonate (0.2 g), ethyl 4-bromobutyrate (0.12 g) in hexamethylphosphoric triamide ml) was stirred at ambient temperature for 1 day. The resulting mixture was poured into ice-water. The appeared precipitates were collected by filtration, washed with water, and recrystallized from ethanol to give 7-chloro-2-[5-(3-ethoxycarbonylpropylamino)benzofuran-2-yl]quinoline (0.13 g).

Provenance & Evidence