HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → HCID 22922151, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 136058237 | HCID 136058237 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 22922151 | HCID 22922151 | 49.1% |
Reaction Steps
A mixture of 7-chloro-2-(5-methoxycarbonyl-3-hydroxybenzofuran-2-yl)quinoline (1.0 g), potassium carbonate (0.39 g), and methyl iodide (0.40 g) in a mixture of tetrahydrofuran (20 ml) and N,N-dimethylformamide (8 ml) was stirred under reflux. After being cooled, the appeared precipitates were collected by filtration and washed with acetone to give 7-chloro-2-(5-methoxycarbonyl-3-methoxybenzofuran-2-yl)quinoline (0.51 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05661159 |
| Source dataset | uspto-grants-1997_08 |
| ORD ID | ord-090213dfaa62473ea318ed1268dbcfc4 |
| Source note | uspto-grants-1997_08 |