HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloroaniline → 2H-Benzimidazol-2-one, 1,3-dihydro-6-chloro-1-(3-chlorophenyl)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloroaniline | HCID 7932 | — |
| Reactant | 2,4-Dichloronitrobenzene | HCID 11899 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Solvent | Ethylene Glycol | HCID 174 | — |
| Product | 2H-Benzimidazol-2-one, 1,3-dihydro-6-chloro-1-(3-chlorophenyl)- | HCID 3061806 | — |
Reaction Steps
A mixture of 50 g of 2,4-dichloro-1-nitrobenzene, 40 ml of 3-chloroaniline and 43 g of anhydrous sodium acetate in 220 ml of ethylene glycol is heated at reflux for 72 hours. After cooling, the precipitate formed is filtered off and washed with water. 39 g of the expected product are obtained after crystallization from iso ether, mp=112° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05661169 |
| Source dataset | uspto-grants-1997_08 |
| ORD ID | ord-3c73c172d22741c494058f4cd544feab |
| Source note | uspto-grants-1997_08 |