Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 225868Generated: October 27, 2026

N,1-dimethylindole-2-carboxamide → [(5-Fluoro-1H-indol-2-yl)methyl]-methylamine

https://huagongshe.com/reaction/225868

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,1-dimethylindole-2-carboxamideHCID 12303315—
ReactantN,1-Dimethyl-5-fluoro-1H-indole-2-carboxamideHCID 22593743—
Product[(5-Fluoro-1H-indol-2-yl)methyl]-methylamineHCID 2259372678%

Reaction Steps

According to the procedure of Preparation 1(c), except substituting N,1-dimethyl-5-fluoro-1H-indole-2-carboxamide for the N,1-dimethyl-1H-indole-2-carboxamide, the title compound (1.5 g, 78%) was prepared as a white solid: MS (ES) m/e 193 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07557125B2
Source datasetuspto-grants-2009_07
ORD IDord-997673523f7447df8a577c44fe3e3856
Source noteuspto-grants-2009_07