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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2259028Generated: October 30, 2026

6-Bromoquinoline → 6-Bromoquinoline

https://huagongshe.com/reaction/2259028

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-BromoquinolineHCID 79243—
Reactant[5-Methyl-1-(oxan-2-yl)-1H-indazol-4-yl]boronic acidHCID 129009568—
ReagentPotassium Phosphate, TribasicHCID 62657—
Catalystpalladium(II) acetateHCID 167845—
Catalyst2-Dicyclohexylphosphino-2',6'-dimethoxybiphenylHCID 11269872—
SolventTetrahydrofuranHCID 8028—
ProductQuinolineHCID 70472.48%
Product6-BromoquinolineHCID 7924370.013%
Product6,6'-BiquinolineHCID 6207110%
ProductHCID 10751213HCID 107512132.096%
Product[5-Methyl-1-(oxan-2-yl)-1H-indazol-4-yl]boronic acidHCID 12900956825.412%
ProductHCID 178422846HCID 1784228460%

Reaction Conditions

Temperature100 °C

Provenance & Evidence

DOI10.1021/jacs.2c08592
Source datasetHTE Suzuki coupling dataset
ORD IDord-23473758417140ffa75f384eb2ba5e23
Source noteHTE Suzuki coupling dataset