Methanesulfonic Acid → HCID 86749134, compound

Participants

Reaction Steps

A 278 mg sample of the purified product from step 22a above was treated according to the procedure of Example 1c (except starting with the methanesulfonic acid instead of HCl/ether) to afford 78 mg of the title product. MS: 209 (M+H)+. NMR (D2O) δ: 2.70 (q, 2H, J=8.1 Hz), 2.80(s, 3H), 4.08-4.18 (m, 2H), 4.46 (d, 2H, J=4.0 Hz), 4.90-4.96 (m, 1H), 7.45-7.49 (m, 1H), 7.60 (t, 1H, 8.4 Hz), 7.90 (t, 1H, 2.4), 7.93-7.96 (m, 1H). Anal. Calcd for C10H12ClN2O3.1.16 CH3SO3H: C, 34.60; H, 5.21; N, 5.93; Found: C, 34.25; H, 5.25; N, 6.08.

Provenance & Evidence