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HRID2259215

反应详情

EQUATION

反应方程式

HRID 2259215 的结构方程式

REACTANTS

反应物

2
结构：CN(C)CCOc1ccc(C(=O)O)cc1
HCID6486619

4-(2-Dimethylamino-ethoxy)-benzoic acid

C11H15NO3

结构：COc1ccc2cc(C3CCCC3)sc2c1
HCID19002796

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc2c(C(=O)c3ccc(OCCN(C)C)cc3)c(C3CCCC3)sc2c1
HCID19424255

未命名化合物

收率 42.7%

PROCEDURE

实验过程

The same operations as in Preparation example 6 were carried out using 200 mg of 4-[2-(dimethylamino)ethoxy]benzoic acid in place of 4-(2-chloroethoxy)benzoic acid and 45 mg of 6-methoxy-2-cyclopentylbenzo[b]thiophene in place of 6-methoxy-2-cyclohexylbenzo[b]thiophene, and then purification was carried out by TLC (developing solvent, chloroform:methanol=19:1) to obtain 35 mg of (6-methoxy-2-cyclopentylbenzo[b]thien-3-yl)[4-[2-(dimethylamino)ethoxy]phenyl]methanone.

WORKUP

后处理

  1. customThe same operations as in Preparation example 6
  2. custompurification