HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 19003219, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 1-Naphthalenesulfonyl chloride | HCID 66560 | — |
| Reactant | HCID 178479278 | HCID 178479278 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 19003219 | HCID 19003219 | 89% |
Reaction Steps
To 18.6 g of trans-4-aminocyclohexanol hydrochloride suspended in 700 ml of chloroform are added, at 5° C., 34 ml of triethylamine, followed by a solution containing 18.6g of 1-naphthylsulfonyl chloride in 100 ml of chloroform. After reacting for 15 hours, the reaction mixture is poured onto 500 ml of water. The expected product is obtained by filtration of the precipitate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05472979 |
| Source dataset | uspto-grants-1995_12 |
| ORD ID | ord-e278dd7f9ae742e490e3df1bea4c0827 |
| Source note | uspto-grants-1995_12 |