HuagongsheHuagongshe Chemistry Print Report · For research reference only
Citraconic Anhydrides → HCID 86748897, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Citraconic Anhydrides | HCID 12012 | — |
| Reactant | O-methyl-L-tyrosine N-Methylamide | HCID 14303038 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 86748897 | HCID 86748897 | 26% |
Reaction Steps
A mixed solution consisting of 50 g of N,O-dimethyltyrosine amide, 400 ml of dry chloroform and 27 g of citraconic anhydride was stirred at room temperature for 6 hours, concentrated under a reduced pressure, subjected to a silica gel column chromatography and eluted with chloroform-methanol-acetic acid to obtain 20 g of Nα -(3-carboxy-2-butenoyl)-N,O-dimethyltyrosine amide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05473100 |
| Source dataset | uspto-grants-1995_12 |
| ORD ID | ord-9b34aeb2d6ef4b6cba36f73439b557c6 |
| Source note | uspto-grants-1995_12 |