HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isophthalaldehyde → 3-(2-(7-Chloroquinolin-2-yl)vinyl)benzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isophthalaldehyde | HCID 34777 | — |
| Reactant | 7-Chloro-2-methylquinoline | HCID 138395 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | Acetic Anhydride | HCID 7918 | — |
| Product | 3-(2-(7-Chloroquinolin-2-yl)vinyl)benzaldehyde | HCID 53394853 | — |
Reaction Steps
A solution of isophthalaldehyde (4.0 g) and 7-chloroquinaldine (5.39 g) in acetic anhydride was heated at 125° in an oil bath for 48 hours. The reaction was cooled to room temperature, diluted with ether (30 mL) and the resulting suspension was stirred vigorously. The solid title compound was collected by filtration and was used as such in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05428171 |
| Source dataset | uspto-grants-1995_06 |
| ORD ID | ord-82aa24b70650476f8934154e035255ed |
| Source note | uspto-grants-1995_06 |