Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Trichloroisocyanuric Acid | HCID 6909 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 5-Methyl-2-trimethylsilanyl-furo[3,2-b]pyridine | HCID 11435674 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | HCID 19002930 | HCID 19002930 | 96% |
Reaction Steps
To a solution of 2-trimethylsilyl-5-methylfurano[3,2-b]pyridine (1.05 g, 5.15 mmol) in CH2Cl2 (16 mL) at 0° C. was added trichloroisocyanuric acid (1.2 g, 5.15 mmol). The mixture was stirred at 0° C. for 30 rain and then at r.t. for 20 hr. A solution of 30% EtOAc in hexane was added. The resulting mixture was filtered through a short bed of silica gel and eluted with more 30% EtOAc in hexane. Evaporation of the filtrate gave 1.0 g (96%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05472964 |
|---|
| Source dataset | uspto-grants-1995_12 |
|---|
| ORD ID | ord-0b2b9cb5b35d403da2a02636feebfe8b |
|---|
| Source note | uspto-grants-1995_12 |
|---|
