HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → HCID 13617479, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | Methyl 3-oxohexanoate | HCID 121700 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 13617479 | HCID 13617479 | — |
Reaction Steps
Methyl 3-ketohexanoate (44.7 g, 310 mmol) was diluted with methanol (75 mL) and 0.2N HCl (2 mL). Et2NH2 +Ru2Cl5- (BINAP)2 (200 mg) was added and the mixture was heated at 60° under 100 psi of hydrogen for 2 hours. Toluene (100 mL) was added and the mixture was concentrated to an oil weighing 75 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05474919 |
| Source dataset | uspto-grants-1995_12 |
| ORD ID | ord-bf4ad669535e4b6bb8ac83d470e73da0 |
| Source note | uspto-grants-1995_12 |