Nitric Acid → 2-Chloro-6-nitrobenzothiazole

HRID 2259645Notes

Reaction equation

HRID 2259645 reaction equation
[Cl:1][C:2]1[S:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1.[N+:11]([O-])([OH:13])=[O:12]>S(=O)(=O)(O)O>[Cl:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([N+:11]([O-:13])=[O:12])[CH:8]=[CH:7][C:5]=2[N:6]=1

Participants

4

Reactant 2

HCID 944Nitric AcidHCID 119872-Chlorobenzothiazole

Product 1

HCID 754762-Chloro-6-nitrobenzothiazole

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

300 g of 2-chlorobenzothiazole was dissolved in 1500 ml of concentrated sulfuric acid and then 134 ml of concenrated nitric acid was added dropwise to the solution at 0° to 10° C. After stirring for 1 h, the reaction mixture was poured into ice/water. The precipitates thus obtained were recovered by filtration, washed with water and then with acetone, and dried to give 380 g of the titled compound.

Workup

  1. customThe precipitates thus
  2. customobtained
  3. filtrationwere recovered by filtration
  4. washwashed with water
  5. dry with materialwith acetone, and dried

Sources & evidence

ORD record
ord-ec6d8194c5a54c2e9224f05bad93b611
Source dataset
uspto-grants-1995_12
Patent number
US05475014

Reaction notes

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