HCID 19001524, compound → HCID 15342531, compound

Participants

Reaction Steps

60 g of the N-(6-nitrobenzothiazol-2-yl)-4-cyanopiperidine obtained in the Preparation Example 13 was dissolved in 2,000 ml of dioxane and hydrogenated in the presence of 3 g of a 10% palladium/carbon catalyst at room temperature under atmospheric pressure for 2 h. Then the catalyst was removed by filtration and the solution was concentrated under reduced pressure to give 51 g of the titled compound.

Provenance & Evidence