Sodium Hydroxide → HCID 15342514, compound

Participants

Reaction Steps

4.7 g of the 3-(2-benzoyloxymethylbenzothiazol-6-yl)-5-methoxymethyl-2-oxazolidinone obtained in the Example 1 was dissolved in methanol/dioxane (1:1) solvent. 7.5 ml of a 2N NaOH aqueous solution was added to the solution and the mixture was stirred for 2 h. Methanol was removed under reduced pressure and then water was added to the residue. After extraction with ethyl acetate followed by drying over sodium sulfate, the solution was concentrated under reduced pressure to give 3.25 g of the titled compound.

Provenance & Evidence