Ammonia → HCID 17876736, compound

HRID 2259725Notes

Reaction equation

HRID 2259725 reaction equation
[NH3:1].[NH2:2][C:3]1[C:8]([C:9](=[O:17])[C:10]2[CH:15]=[CH:14][C:13]([Br:16])=[CH:12][CH:11]=2)=[CH:7][CH:6]=[CH:5][C:4]=1[CH2:18][C:19]([O:21]CC)=O>>[NH2:2][C:3]1[C:8]([C:9](=[O:17])[C:10]2[CH:15]=[CH:14][C:13]([Br:16])=[CH:12][CH:11]=2)=[CH:7][CH:6]=[CH:5][C:4]=1[CH2:18][C:19]([NH2:1])=[O:21]

Participants

3

Reactant 2

HCID 222AmmoniaHCID 13577658HCID 13577658, compound

Product 1

HCID 17876736HCID 17876736, compound

Procedure

Ammonia is condensed in a tube containing 2-amino-3-(4-bromobenzoyl)benzeneacetic acid, ethyl ester. The tube is sealed and the reaction mixture is warmed. The sealed tube was cooled and opened. Solvent was evaporated and the residue was purified by standard methods to give Compound 15.

Workup

  1. customcondensed in a tube
  2. customThe tube is sealed
  3. temperaturethe reaction mixture is warmed
  4. temperatureThe sealed tube was cooled
  5. customSolvent was evaporated
  6. customthe residue was purified by standard methods

Sources & evidence

ORD record
ord-d0478842effc4fb4abf26407df9f53d6
Source dataset
uspto-grants-1995_12
Patent number
US05475034

Reaction notes

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