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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2259922Generated: October 31, 2026

2-Chloro-5-trichloromethylpyridine → 2-Chloro-5-(chloromethyl)pyridine

https://huagongshe.com/reaction/2259922

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-trichloromethylpyridineHCID 50293—
CatalystZincHCID 23994—
Product2-Chloro-5-(chloromethyl)pyridineHCID 155479—

Reaction Steps

The method according to claim 1, wherein 2-chloro-5-trichloromethylpyridine is reduced at a reaction temperature of from -20° C. to +100° C. with from 2 to 4 equivalents of the proton donor and from 2 to 4 equivalents of zinc, relative to 1 mol of 2-chloro-5-trichloromethylpyridine and from 0.5 to 50 parts by weight of the solvent, relative to 1 mol of 2-chloro-5-trichloromethylpyridine, to obtain 2-chloro-5chloromethylpyridine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05475112
Source datasetuspto-grants-1995_12
ORD IDord-6ad239d61f9a42ff8d79de4291a145c4
Source noteuspto-grants-1995_12