Phthalic Anhydride → HCID 9930580, compound

Participants

Reaction Steps

A 8.3 ml (60 mmol) quantity of triethylamine was added to a solution of 12.35 g (50 mmol) of [1-(4-t-butylphenyl)-2-pyrrolidone-4-yl)methyl alcohol (III) and 7.4 g (50 mmol) of phthalic anhydride in dichloromethane (150 ml), and the mixture was refluxed with heating for 24 hours. The reaction mixture was washed with a dilute hydrochloric acid, dried over magnesium sulfate and concentrated under reduced pressure to give 19.8 g (quantitative yield) of the title compound.

Provenance & Evidence