HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Tolyl isocyanate → tert-butyl 2-{N-(4-methoxyphenyl)-2-[3-(3-methylphenyl)ureido]acetamido}-acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Tolyl isocyanate | HCID 69303 | — |
| Reactant | HCID 19001938 | HCID 19001938 | — |
| Product | tert-butyl 2-{N-(4-methoxyphenyl)-2-[3-(3-methylphenyl)ureido]acetamido}-acetate | HCID 19002044 | 17.7% |
Reaction Steps
Using a procedure similar to that described in Example 1, but starting with tert-butyl 2-[2-amino-N-(4-methoxyphenyl)acetamido]acetate (6.6 g) and 3-methylphenyl isocyanate (3 g), and after recrystallisation in acetonitrile, tert-butyl 2-{N-(4-methoxyphenyl)-2-[3-(3-methylphenyl)ureido]acetamido}-acetate (1.7 g), m.p. 158° C., is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05475106 |
| Source dataset | uspto-grants-1995_12 |
| ORD ID | ord-b1158faff6054c72a6088eab4ba61a6a |
| Source note | uspto-grants-1995_12 |